Zyphra says its ZOE serving system speeds up GLM-5.3-Flash on AMD MI300X
Overview
Zyphra says it now serves Z.ai's GLM-5.3-Flash on Zyphra Inference using its Zyphra Optimization Engine (ZOE) on AMD Instinct MI300X GPUs.
Zyphra claims ZOE delivers 3.1x faster p90 generation per user and 10.7x lower p90 time to first token than stock SGLang at 64 concurrent sessions.
In a SemiAnalysis AgentX replay of multi-turn coding agent sessions on one 8xMI300X node, Zyphra reports 52.8 tokens/s per user for ZOE versus 16.9 tokens/s for stock SGLang at 64 sessions. The company also reports p90 time to first token of 2.9 s for ZOE and 31.4 s for stock SGLang.
Zyphra further says ZOE makes serving GLM-5.3-Flash on MI300X profitable, earning $2.95 per hour per GPU after $2.02 per hour in rent at 64 sessions per node, compared with $0.13 per hour for stock SGLang. Zyphra says it runs 64 sessions rather than 96 because p90 time to first token rises from 2.9 s to 21.8 s at 96 sessions. These are Zyphra's own benchmark claims.
Written by AI from the articles below · updated Nov 5, 2:59 PM ET
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Developments
4 developments
- Nov 5, 2:51 PM ET · 1 articleZyphra reports ZOE serving economics on MI300XZyphra: Zyphra's ZOE makes GLM-5.3-Flash on MI300X profitable at 64 sessions
- Nov 5, 2:51 PM ET · 1 articleZyphra reports ZOE time-to-first-token benchmark resultZyphra: Zyphra's ZOE cuts p90 time to first token 10.7x versus stock SGLang
- Nov 5, 2:51 PM ET · 1 articleZyphra reports ZOE generation speed on AgentXZyphra: Zyphra's ZOE runs 3.1x faster per user than stock SGLang on AgentX
- Nov 5, 2:51 PM ET · 1 articleZyphra Inference adds support for GLM-5.3-FlashZyphra: Zyphra adds GLM-5.3-Flash to Zyphra Inference on AMD MI300X
Article timeline
The articles in this story. Times are ET.
Zyphra@ZyphraAIOfficialZyphra's ZOE makes GLM-5.3-Flash on MI300X profitable at 64 sessionsAIZyphra says its ZOE serving system makes GLM-5.3-Flash on MI300X profitable, earning $2.95 per hour per GPU after $2.02/hr rent at 64 sessions per node. Stock SGLang earns $0.13 per hour under the same conditions. Running 96 sessions earns more, but p90 time to first token rises from 2.9s to 21.8s, so Zyphra runs 64.

Zyphra@ZyphraAIOfficialZyphra's ZOE cuts p90 time to first token 10.7x versus stock SGLangAIZyphra says ZOE has 10.7x lower p90 time to first token than stock SGLang at 64 concurrent sessions. The post reports ZOE at 2.9 s and stock SGLang at 31.4 s.

Zyphra@ZyphraAIOfficialZyphra adds GLM-5.3-Flash to Zyphra Inference on AMD MI300XAIZyphra says GLM-5.3-Flash from Z.ai is now served on Zyphra Inference using its Zyphra Optimization Engine (ZOE) on AMD Instinct MI300X. Zyphra claims ZOE makes p90 generation 3.1x faster per user and p90 time to first token 10.7x lower than stock SGLang.

Zyphra@ZyphraAIOfficialZyphra's ZOE runs 3.1x faster per user than stock SGLang on AgentXAIZyphra says its ZOE generates 3.1x faster per user than stock SGLang on one 8xMI300X node in the SemiAnalysis AgentX replay of multi-turn coding agent sessions. At 64 concurrent sessions, ZOE reaches 52.8 tokens/s per user at p90 generation speed, versus 16.9 tokens/s for stock SGLang.

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