# Google DeepMind's AlphaGenome 2 spots cell-type-specific gene regulation mutations

> Original title: Looking at a whole tissue at once is like looking at a blurry image: you get the visuals, but miss what’s happening inside individual pix...

- Source: Google DeepMind
- Published: 2026-11-11T15:03:18.000Z
- Bad Influence: https://badinfluence.news/items/u2f40y5kgq95ormucyvtsvnq1
- Original: https://x.com/GoogleDeepMind/status/2120532826336501822

## Summary

Google DeepMind says AlphaGenome 2, trained on over 100M profiles across 68 tissues, analyzes one cell type at a time. It identifies nearly twice as many mutations that turn genes on and off as its previous model.

## Post

Looking at a whole tissue at once is like looking at a blurry image: you get the visuals, but miss what’s happening inside individual pixels.

Trained on 100M+ profiles across 68 tissues, AlphaGenome 2 focuses on one cell type at a time, spotting nearly twice as many mutations that turn genes on and off as our previous model.

[Video](https://badinfluence.news/api/img-proxy?u=https%3A%2F%2Fpbs.twimg.com%2Ftweet_video_thumb%2FHW2ktajXwAAYq7h.jpg&mode=thumb&exp=1794700800&sig=c51e2eef7cecb9f3)